The paper discusses the problems associated with environmental modelling and the need to develop simple, ‘top-down’, stochastic models that match the information content of the data. It introduces the concept of Data-Based Mechanistic (DBM) modelling and contrasts its inductive approach with the hypotheticodeductive approaches that dominate most environmental modelling research at the present t...

Demineralized bone matrix (DBM) is one of the most widely used bone graft materials in dentistry. However, the ability of DBM to reliably and predictably induce bone regeneration has always been a cause for concern. The quality of DBM varies greatly depending on several donor dependent factors and also manufacturing techniques. In order to standardize the quality and to enable reliable and pred...

INTRODUCTION Demineralised bone matrix (DBM) is an allograft material widely used as a bone filler and bone graft substitute. DBM contains bone morphogenetic proteins (BMPs), which induce and regulate bone formation during embryogenesis and in postnatal life. AIMS AND OBJECTIVES To investigate the osteoinductivity of DBM augmented with xenogeneic BMP-complex at different doses. MATERIALS AN...

Dibenzoylmethane (DBM) has been shown to exert a variety of beneficial effects on human health. However, the mechanism of action is poorly understood. In this study, DBM increased phosphorylation of AMP-activated protein kinase (AMPK) and stimulated glucose uptake in a skeletal muscle cell line. Both knockdown of AMPK with siRNA and inhibition with AMPK inhibitor blocked DBM-induced glucose upt...

The diamondback moth Genome Database (DBM-DB) is a central online repository for storing and integrating genomic data of diamondback moth (DBM), Plutella xylostella (L.). It provides comprehensive search tools and downloadable datasets for scientists to study comparative genomics, biological interpretation and gene annotation of this insect pest. DBM-DB contains assembled transcriptome datasets...

A precipitation-temperature-flow model is developed to compute flow from raw precipitation records, taking into consideration snow-melt contribution to the flow. The model does not require other measurements than flow, temperature and raw precipitation, thus resulting particularly useful in all those situations, the majority, where these are the only observed data. A Data-Based Mechanistic (DBM...